Article
The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis.
British journal of cancer - 17 Jan 2005
Mascaux C, Iannino N, Martin B, Paesmans M, Berghmans T, Dusart M, Haller A, Lothaire P, Meert A-P, Noel S, Lafitte J-J, Sculier J-P
Abstract excerpt
The proto-oncogene RAS, coding for a 21 kDa protein (p21), is mutated in 20% of lung cancer. However, the literature remains controversial on its prognostic significance for survival in lung cancer. We performed a systematic review of the literature with meta-analysis to assess its possible prognostic value on survival. Published studies on lung cancer assessing prognostic value of RAS mutation or p21...
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