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Article

Oncogenic role of <i>NALP7</i> in testicular seminomas

1 Dec 2004

Abstract excerpt

To isolate novel molecular targets for treatment of testicular germ cell tumor (TGCT), we performed genome-wide expression profile analysis of testicular seminomas using a cDNA microarray. We here report identification of NACHT, leucine-rich repeat and PYD containing 7 (NALP7 ), that was significantly transactivated in testicular seminomas. Subsequent semi-quantitative RT-PCR and northern blot analyses confirmed...

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PMID: 15596043
DOI: 10.1111/j.1349-7006.2004.tb03182.x

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