Article
Human papillomavirus type 16 E5 protein colocalizes with the antiapoptotic Bcl-2 protein.
Archives of virology - 1 Sept 2004
Auvinen E, Alonso A, Auvinen P
Abstract excerpt
Human papillomavirus type 16 E5 protein contributes to cellular transformation by increasing the mitogenic stimulus from growth factor receptors to the nucleus. In order to study the biological mechanisms of the E5 protein we performed site-directed mutagenesis of the E5 gene. Wild-type as well as mutant E5 proteins were transiently expressed in human cervical epithelial cells, and cell morphology, expression of...
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