Article
Preferential transmission and association of the -403 G --> A promoter RANTES polymorphism with atopic asthma.
Genes and immunity - 1 Feb 2005
Al-Abdulhadi S A, Helms P J, Main M, Smith O, Christie G
Abstract excerpt
Asthma is a complex inherited disease. The study was undertaken to identify the association of RANTES promoter polymorphisms with atopy and asthma using family-based association tests (FBATs) and generation-specific case-control analyses. We identified 154 nuclear families (453 individuals) in whom we established RANTES promoter status using the RFLP-PCR method. Of the two known promoter polymorphisms -403G/A and...
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