Article
Saccharomyces cerevisiae Aqr1 is an internal-membrane transporter involved in excretion of amino acids.
Eukaryotic cell - 1 Dec 2004
Velasco Isabel, Tenreiro Sandra, Calderon Isabel L, André Bruno
Abstract excerpt
Excretion of amino acids by yeast cells was reported long ago but has not been characterized in molecular terms. It is typically favored by overproduction of the amino acid and/or impairment of its uptake. Here we describe the construction of a yeast strain excreting threonine and homoserine. Using this excretor strain, we then applied a reverse-genetics approach and found that the transporter encoded by the...
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