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Article

Antigenic divergence suggested by correlation between antigenic variation and pulsed-field gel electrophoresis profiles of Bordetella pertussis isolates in Japan.

Journal of clinical microbiology - 1 Dec 2004

Kodama Atsuko, Kamachi Kazunari, Horiuchi Yoshinobu, Konda Toshifumi, Arakawa Yoshichika

Abstract excerpt

Antigenic divergence has been found between Bordetella pertussis vaccine strains and circulating strains in several countries. In the present study, we analyzed B. pertussis isolates collected in Japan from 1988 to 2001 using pulsed-field gel electrophoresis (PFGE) and sequencing of two virulence-associated proteins. The 107 isolates were classified into three major groups by PFGE analysis; 87 (81%) were type A,...

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Identifiers

PMID: 15583264
DOI: 10.1128/JCM.42.12.5453-5457.2004
PMCID: PMC535240

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Source receipt: pubmed, retrieved 7 Sept 2026.

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