Article
A family study of alcohol dependence: coaggregation of multiple disorders in relatives of alcohol-dependent probands.
Archives of general psychiatry - 1 Dec 2004
Nurnberger John I, Wiegand Ryan, Bucholz Kathleen, O'Connor Sean, Meyer Eric T, Reich Theodore, Rice John, Schuckit Marc, King Lucy, Petti Theodore, Bierut Laura, Hinrichs Anthony L, Kuperman Samuel, Hesselbrock Victor, Porjesz Bernice
Abstract excerpt
BACKGROUND: Alcohol dependence tends to aggregate within families. We analyzed data from the family collection of the Collaborative Study on the Genetics of Alcoholism to quantify familial aggregation using several different criterion sets. We also assessed the aggregation of other psychiatric disorders in the same sample to identify areas of possible shared genetic vulnerability. DESIGN: Age-corrected lifetime...
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