Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Human melastatin 1 (TRPM1) is regulated by MITF and produces multiple polypeptide isoforms in melanocytes and melanoma

1 Dec 2004

Abstract excerpt

Melastatin 1 (MLSN1), originally identified as melanoma metastasis suppressor, represents a TRPM subfamily of transient receptor potential (TRP) proteins which serve diverse biological roles in a wide variety of cell types. Down-regulation of MLSN1 expression in human cutaneous melanoma, as indicated by in situ hybridization, appears to be a prognostic marker for melanoma metastasis. However, the exact...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ion Channels and Receptors
Share to melanin and skin pigmentation
Share to Phytochemicals and Antioxidant Activities

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15577322
DOI: 10.1097/00008390-200412000-00011

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Human melastatin 1 (TRPM1) is regulated by MITF and produces multiple polypeptide isoforms in melanocytes and melanomaPMID 15577322Read ↗

TRPM1: new trends for an old TRP.Semantic proximity Read ↗

The correlation of TRPM1 (Melastatin) mRNA expression with microphthalmia‐associated transcription factor (MITF) and other melanogenesis‐related proteins in normal and pathological skin, hair follicles and melanocytic neviSemantic proximity Read ↗

Identification and characterization of MTR1, a novel gene with homology to melastatin (MLSN1) and the trp gene family located in the BWS-WT2 critical region on chromosome 11p15.5 and showing allele-specific expression.Semantic proximity Read ↗

TRPM2 Channels: A Potential Therapeutic Target in Melanoma?Semantic proximity Read ↗

Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters.Semantic proximity Read ↗

Evaluation of the TRPM protein family as potential biomarkers for various types of human cancer using public database analysesSemantic proximity Read ↗

MITF: master regulator of melanocyte development and melanoma oncogene.Semantic proximity Read ↗

Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation.Semantic proximity Read ↗

Identification of a distal enhancer for the melanocyte-specific promoter of the MITF gene.Semantic proximity Read ↗

Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and InvasionSemantic proximity Read ↗

“Transcription physiology” of pigment formation in melanocytes: central role of MITFSemantic proximity Read ↗

Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.