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Article

Chronic exposure to rotenone models sporadic Parkinson's disease in Drosophila melanogaster.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 2004

Coulom Hélène, Birman Serge

Abstract excerpt

Parkinson's disease (PD) is a movement disorder characterized by the selective degeneration of nigrostriatal dopaminergic neurons. Both familial and sporadic cases present tremor, rigidity, slowness of movement, and postural instability. Although major insights into the genes responsible for some rare hereditary cases have arisen, the etiology of sporadic cases remains unknown. Epidemiological studies have...

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Identifiers

PMID: 15574749
DOI: 10.1523/JNEUROSCI.2993-04.2004
PMCID: PMC6730201

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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