Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression of 7a, a Protein Specifically Encoded by the Severe Acute Respiratory Syndrome Coronavirus, Induces Apoptosis via a Caspase-Dependent Pathway

24 Nov 2004

Abstract excerpt

Besides genes that are homologous to proteins found in other coronaviruses, the severe acute respiratory syndrome coronavirus genome also contains nine other potential open reading frames. Previously, we have characterized the expression and cellular localization of two of these "accessory" viral proteins, 3a (previously termed U274) and 7a (previously termed U122). In this study, we further examined whether they...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Animal Virus Infections Studies
Share to SARS-CoV-2 and COVID-19 Research
Share to Viral gastroenteritis research and epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15564512
DOI: 10.1128/jvi.78.24.14043-14047.2004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression of 7a, a Protein Specifically Encoded by the Severe Acute Respiratory Syndrome Coronavirus, Induces Apoptosis via a Caspase-Dependent PathwayPMID 15564512Read ↗

Induction of apoptosis by the severe acute respiratory syndrome coronavirus 7a protein is dependent on its interaction with the Bcl-XL protein.Semantic proximity Read ↗

SARS-CoV-2 Accessory Protein ORF7b Mediates Tumor Necrosis Factor-α-Induced Apoptosis in CellsSemantic proximity Read ↗

Open Reading Frame 8a of the Human Severe Acute Respiratory Syndrome Coronavirus Not Only Promotes Viral Replication but Also Induces ApoptosisSemantic proximity Read ↗

The 3a protein of severe acute respiratory syndrome-associated coronavirus induces apoptosis in Vero E6 cellsSemantic proximity Read ↗

Severe Acute Respiratory Syndrome Coronavirus Gene 7 Products Contribute to Virus-Induced ApoptosisSemantic proximity Read ↗

Over-expression of severe acute respiratory syndrome coronavirus 3b protein induces both apoptosis and necrosis in Vero E6 cellsSemantic proximity Read ↗

The ORF3a protein of SARS-CoV-2 induces apoptosis in cellsSemantic proximity Read ↗

A SARS-CoV protein, ORF-6, induces caspase-3 mediated, ER stress and JNK-dependent apoptosisSemantic proximity Read ↗

The 7a Accessory Protein of Severe Acute Respiratory Syndrome Coronavirus Acts as an RNA Silencing SuppressorSemantic proximity Read ↗

Targeting highly pathogenic coronavirus-induced apoptosis reduces viral pathogenesis and disease severitySemantic proximity Read ↗

SARS coronavirus 7a protein blocks cell cycle progression at G0/G1 phase via the cyclin D3/pRb pathway.Semantic proximity Read ↗

Regulation of cell death during infection by the severe acute respiratory syndrome coronavirus and other coronavirusesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.