Article
Cell-associated episialin is a complex containing two proteins derived from a common precursor.
The Journal of biological chemistry - 25 Mar 1992
Ligtenberg M J, Kruijshaar L, Buijs F, van Meijer M, Litvinov S V, Hilkens J
Abstract excerpt
cDNA for the epithelial sialomucin episialin encodes a transmembrane molecule with a large extracellular domain, which mainly consists of repeats of 20 amino acids. Here we confirm the existence of a previously proposed proteolytic cleavage of episialin that occurs in the endoplasmic reticulum (Hilkens, J., and Buijs, F. (1988) J. Biol. Chem. 263, 4215-4222) and show that a similar cleavage takes place in in...
Topics
- Amino Acid Sequence
- Antibodies
- Antigens, Neoplasm
- Base Sequence
- Breast Neoplasms
- Cell Line
- Chromosome Deletion
- DNA
- Female
- Genetic Variation
- Glucosamine
