Article
Length of Telomeric Repeats in Neuroblastoma: Correlation with Prognosis and Other Biological Characteristics
1 Feb 1992
Abstract excerpt
Telomeres are the physical ends of eukaryotic chromosomes. In view of reports of the reduction of telomeric repeats in human malignant tumors, we measured the lengths of telomeric repeats in 55 primary neuroblastomas. The average lengths of telomeric repeats in these tumors fell in a wide range (from 1.1 kb to more than 23 kb) relative to those in ganglioneuromas and normal peripheral mononuclear cells. The...
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