Article
Prostaglandin FP Agonists Alter Metalloproteinase Gene Expression in Sclera
22 Nov 2004
Abstract excerpt
PURPOSE: The present study was undertaken to determine whether exposure of the sclera to prostaglandin (PG)F(2alpha) or to the PGF(2alpha) analogue latanoprost acid alters mRNA for matrix metalloproteinases. METHOD: Fifteen human eye bank eyes were studied. Circular pieces of sclera were either immediately preserved in a stabilization reagent or cultured in low-serum DMEM/F-12 medium. The cultures were treated...
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