Article
Amplification of the Steroidogenic Factor 1 Gene in Childhood Adrenocortical Tumors
1 Feb 2005
Abstract excerpt
Southern Brazil has one of the highest incidences of childhood adrenocortical tumors (ACTs), occurring 10-15 times more frequently than worldwide estimates. The reasons for this increase remain elusive. In an attempt to further characterize the genetic changes in childhood ACTs, we recently detected a consistent gain of 9q (or a portion of it) in eight of nine cases of pediatric ACTs and amplification of 9q34 in...
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