Article
Highly consistent genetic alterations in childhood adrenocortical tumours detected by comparative genomic hybridization.
British journal of cancer - 1 Sept 1999
James L A, Kelsey A M, Birch J M, Varley J M
Abstract excerpt
We have examined 11 cases of childhood adrenocortical tumours for copy number changes using comparative genomic hybridization (CGH). The changes seen are highly consistent between cases, and are independent of tumour type (carcinoma versus adenoma) or the presence of a germline TP53 mutation. The regions of chromosomal gain and loss identified in this study indicate the location of genes that are potentially...
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