Article
Lipoprotein lipase locus and progression of atherosclerosis in coronary-artery bypass grafts.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Jan 2000
Taylor Kent D, Scheuner Maren T, Yang Huiying, Wang Yaping, Haritunians Talin, Fischel-Ghodsian Nathan, Shah Prediman K, Forrester James S, Knatterud Genell, Rotter Jerome I
Abstract excerpt
PURPOSE: Our aim was to test whether polymorphisms in the lipoprotein lipase (LPL) gene were associated with the progression of atherosclerosis in grafts examined in the Post-Coronary Artery Bypass Graft Trial (Post-CABG Trial). METHODS: 843 subjects in the post-CABG trial were genotyped for the LPL-D9N, N291S, PvuII, (TTTA)n, and HindIII polymorphisms. Associations between genotype and angiographically measured...
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