Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic variation for total fitness in Drosophila melanogaster: complex yet replicable patterns.

Genetics - 1 Mar 2005

Gardner Michael P, Fowler Kevin, Barton Nicholas H, Partridge Linda

Abstract excerpt

The extent of genetic variation in fitness is a crucial issue in evolutionary biology and yet remains largely unresolved. In Drosophila melanogaster, we have devised a method that allows the net effects on fitness of heterozygous wild-type chromosomes to be measured, by competing them against two...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biological Evolution
Share to Chromosomes
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Genes, Lethal

Share to Longevity

Share to Tropomyosin

Source

Open in PubMed Open full text

Identifiers

PMID: 15545656
DOI: 10.1534/genetics.104.032367
PMCID: PMC1449528

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15545656-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic variation for total fitness in Drosophila melanogaster: complex yet replicable patterns.PMID 15545656Read ↗

Measuring fitness by means of balancer chromosomes.Semantic proximity Read ↗

Genetic variation for total fitness in Drosophila melanogaster.Semantic proximity Read ↗

Additive genetic variance for fitness maintained by balancing selection.Semantic proximity Read ↗

Factors affecting the genetic load in Drosophila: synergistic epistasis and correlations among fitness components.Semantic proximity Read ↗

Genotype-environment interaction for total fitness in Drosophila.Semantic proximity Read ↗

Quantifying the fraction of new mutations that are recessive lethal.Semantic proximity Read ↗

A century of theories of balancing selectionSemantic proximity Read ↗

Resampling the pool of genotypic possibilities: an adaptive function of sexual reproduction.Semantic proximity Read ↗

Quantifying the fraction of new mutations that are recessive lethalSemantic proximity Read ↗

Hidden epistastic interactions can favour the evolution of sex and recombination.Semantic proximity Read ↗

Genetic incompatibilities are widespread within species.Semantic proximity Read ↗

Variability in fitness effects and the limitations of fitness optimizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.