Article
A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans.
Development (Cambridge, England) - 1 Dec 2004
Davis M Wayne, Birnie Andrew J, Chan Aubrey C, Page Antony P, Jorgensen Erik M
Abstract excerpt
Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a Caenorhabditis elegans metalloprotease gene, nas-37, that cause incomplete ecdysis. At each molt the cuticle fails to open sufficiently at the anterior end and the...
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