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Article

A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans.

Development (Cambridge, England) - 1 Dec 2004

Davis M Wayne, Birnie Andrew J, Chan Aubrey C, Page Antony P, Jorgensen Erik M

Abstract excerpt

Molting is required for progression between larval stages in the life cycle of nematodes. We have identified four mutant alleles of a Caenorhabditis elegans metalloprotease gene, nas-37, that cause incomplete ecdysis. At each molt the cuticle fails to open sufficiently at the anterior end and the partially shed cuticle is dragged behind the animal. The gene is expressed in hypodermal cells 4 hours before ecdysis...

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Identifiers

PMID: 15539494
DOI: 10.1242/dev.01454

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A conserved metalloprotease mediates ecdysis in Caenorhabditis elegans.PMID 15539494Read ↗

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