Article
Cohort analysis of a single nucleotide polymorphism on DNA chips.
Biosensors & bioelectronics - 15 Nov 2004
Schwonbeck Susanne, Krause-Griep Andrea, Gajovic-Eichelmann Nenad, Ehrentreich-Förster Eva, Meinl Walter, Glatt Hansrüdi, Bier Frank F
Abstract excerpt
A method has been developed to determine SNPs on DNA chips by applying a flow-through bioscanner. As a practical application we demonstrated the fast and simple SNP analysis of 24 genotypes in an array of 96 spots with a single hybridisation and dissociation experiment. The main advantage of this methodical concept is the parallel and fast analysis without any need of enzymatic digestion. Additionally, the DNA...
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