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Iron trafficking in the mitochondrion: novel pathways revealed by disease

5 Nov 2004

Abstract excerpt

It is well known that iron (Fe) is transported to the mitochondrion for heme synthesis. However, only recently has the importance of this organelle for many other facets of Fe metabolism become widely appreciated. Indeed, this was stimulated by the description of human disease states that implicate mitochondrial Fe metabolism. In particular, studies assessing various diseases leading to mitochondrial Fe loading...

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PMID: 15528311
DOI: 10.1182/blood-2004-10-3856

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