Article
Molecular characterization of conditionally immortalized cell lines derived from mouse early embryonic inner ear.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Dec 2004
Germiller John A, Smiley Elizabeth C, Ellis Amanda D, Hoff Jessica S, Deshmukh Ian, Allen Susan J, Barald Kate F
Abstract excerpt
Inner ear sensory hair cells (HCs), supporting cells (SCs), and sensory neurons (SNs) are hypothesized to develop from common progenitors in the early embryonic otocyst. Because little is known about the molecular signals that control this lineage specification, we derived a model system of early otic development: conditionally immortalized otocyst (IMO) cell lines from the embryonic day 9.5 Immortomouse. This...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
