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Article

Evolutionary dynamics of insertion sequences in Helicobacter pylori.

Journal of bacteriology - 1 Nov 2004

Kalia Awdhesh, Mukhopadhyay Asish K, Dailide Giedrius, Ito Yoshiyki, Azuma Takeshi, Wong Benjamin C Y, Berg Douglas E

Abstract excerpt

Prokaryotic insertion sequence (IS) elements behave like parasites in terms of their ability to invade and proliferate in microbial gene pools and like symbionts when they coevolve with their bacterial hosts. Here we investigated the evolutionary history of IS605 and IS607 of Helicobacter pylori, a genetically diverse gastric pathogen. These elements contain unrelated transposase genes (orfA) and also a homolog...

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Identifiers

PMID: 15516562
DOI: 10.1128/JB.186.22.7508-7520.2004
PMCID: PMC524885

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