Article
Beta-catenin is involved in insulin-like growth factor 1-mediated transactivation of the androgen receptor.
Molecular endocrinology (Baltimore, Md.) - 1 Feb 2005
Verras Meletios, Sun Zijie
Abstract excerpt
The androgen-signaling pathway is important for the growth and progression of prostate cancer cells. IGF-I and other polypeptide growth factors have been shown to be capable of induction of androgen receptor (AR) activation in the absence of, or at low levels of, ligand. It has been shown that IG...
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