Article
DNA binding factors which interact with the Sp1 site of the chicken delta 1-crystallin promoter are developmentally regulated.
Biochemical and biophysical research communications - 16 Mar 1992
Alemany J, Klement J F, Borrás T, De Pablo F
Abstract excerpt
Transcription of the delta 1-crystallin gene is developmentally regulated in the embryonic chicken lens. Previous work defined a positive transcription regulatory element between positions -120 and -43 of the delta 1-crystallin promoter. This region contains a putative Sp1 binding site (-78 to -7...
Topics
- Aging
- Animals
- Base Sequence
- Binding, Competitive
- Cell Nucleus
- Chick Embryo
- Crystallins
- DNA-Binding Proteins
- Gene Expression Regulation
- Lens, Crystalline
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Mutation
- Promoter Regions, Genetic
