Article
DNA binding factors which interact with the Sp1 site of the chicken delta 1-crystallin promoter are developmentally regulated.
Biochemical and biophysical research communications - 16 Mar 1992
Alemany J, Klement J F, Borrás T, De Pablo F
Abstract excerpt
Transcription of the delta 1-crystallin gene is developmentally regulated in the embryonic chicken lens. Previous work defined a positive transcription regulatory element between positions -120 and -43 of the delta 1-crystallin promoter. This region contains a putative Sp1 binding site (-78 to -71), adjacent to a CAAT box (-70 to -67). Gel retardation assays using lens nuclear extracts revealed two protein-DNA...
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