Article
Maternal microchimerism in underlying pathogenesis of biliary atresia: quantification and phenotypes of maternal cells in the liver.
Pediatrics - 1 Mar 2008
Muraji Toshihiro, Hosaka Naoki, Irie Naoki, Yoshida Makiko, Imai Yukihiro, Tanaka Kohichi, Takada Yasutsugu, Sakamoto Seisuke, Haga Hironori, Ikehara Susumu
Abstract excerpt
OBJECTIVE: The goal was to examine whether microchimerism plays a crucial role in the pathogenesis of biliary atresia; we analyzed the localization of maternal microchimeric cells and their phenotypes. METHODS: Liver biopsy specimens from 8 male infants with biliary atresia and 6 control subjects with other liver diseases were investigated for maternal chimeric cells and their phenotypes through double-staining...
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