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Article

Toll-like receptor 4 gene polymorphisms and susceptibility to juvenile idiopathic arthritis.

Annals of the rheumatic diseases - 1 May 2005

Lamb R, Zeggini E, Thomson W, Donn R

Abstract excerpt

OBJECTIVES: To determine if polymorphisms within the Toll-like receptor 4 (TLR4) gene are associated and linked with juvenile idiopathic arthritis (JIA). To investigate any possible gene-gene (epistatic) interaction between TLR4 and macrophage migration inhibitory factor (MIF) gene polymorphisms. METHODS: 313 simplex families (each containing one affected JIA proband) were genotyped. Two known functionally...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 15498795
DOI: 10.1136/ard.2004.026930
PMCID: PMC1755476

Genes

TLR4
MIF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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