Article
Role of the nuclear matrix proteins in malignant transformation and cancer diagnosis.
Experimental oncology - 1 Sept 2004
Sjakste Nikolajs, Sjakste Tatjana, Vikmanis Uldis
Abstract excerpt
The nuclear matrix (NM) is the structural framework of the nucleus that consists of the peripheral lamins and pore complexes, an internal ribonucleic protein network, and residual nucleoli. Differences between the nuclear matrix protein (NMP) composition of transformed cells and their normal homologues were detected in numerous cases. Actually several tumor-specific nuclear matrix proteins (NMPs) are proposed for...
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