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Article

Labor and Inflammation Increase the Expression of Oxytocin Receptor in Human Amnion1

7 Oct 2010

Abstract excerpt

The oxytocin/oxytocin receptor (OXT/OXTR) system plays an important role in the regulation of parturition. The amnion is a major source of prostaglandins and inflammatory cytokine synthesis, which increase both before and during labor. Amnion is a noncontractile tissue; therefore, the role played by OXT/OXTR in this tissue will be fundamentally different from the role played in myometrial contractions. In the...

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PMID: 20926803
DOI: 10.1095/biolreprod.110.086785

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