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Article

Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers.

International journal of oncology - 1 Nov 2004

Sasamoto Hiromi, Nagasaka Takeshi, Notohara Kenji, Ozaki Kazuhide, Isozaki Hiroshi, Tanaka Noriaki, Matsubara Nagahide

Abstract excerpt

H19 and IGF2 genes are imprinted genes and expressed differently depending on whether they are carried by a chromosome of maternal or paternal origin; H19 is expressed only from the maternal allele and IGF2 only from the paternally inherited allele. The upstream promoter region of H19 has the imprinting-control region (ICR) or CTCF binding sites, where the methylation status of this region is critical to the...

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Identifiers

PMID: 15492815

Genes

IGF2
CTCF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Allele-specific methylation analysis on upstream promoter region of H19 by methylation-specific PCR with confronting two-pair primers.PMID 15492815Read ↗

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