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Article

Molecular basis of the indole-negative reaction in Shigella strains: extensive damages to the tna operon by insertion sequences.

Journal of bacteriology - 1 Nov 2004

Rezwan Ferdousi, Lan Ruiting, Reeves Peter R

Abstract excerpt

The molecular basis of the loss of tryptophan utilization (indole-negative phenotype) of Shigella strains, in effect clones of Escherichia coli, was investigated. Analysis of the tna operon of 23 Shigella strains representing each of the indole-negative serotypes revealed that insertion sequence-mediated insertion and/or deletions damaged the tna operon, leading to inability to convert tryptophan to indole. These...

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Identifiers

PMID: 15489459
DOI: 10.1128/JB.186.21.7460-7465.2004
PMCID: PMC523188

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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