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Article

Early- versus late-onset obsessive-compulsive disorder: investigating genetic and clinical correlates.

Psychiatry research - 30 Sept 2004

Hemmings Sîan M J, Kinnear Craig J, Lochner Christine, Niehaus Dana J H, Knowles James A, Moolman-Smook Johanna C, Corfield Valerie A, Stein Dan J

Abstract excerpt

There is increasing evidence that obsessive-compulsive disorder (OCD) is mediated by genetic factors. Although the precise mechanism of inheritance is unclear, recent evidence has pointed towards the involvement of the serotonergic and dopaminergic systems in the disorder's development. Furthermore, early-onset OCD appears to be a subtype that exhibits distinct clinical features and that is associated with...

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Identifiers

PMID: 15488960
DOI: 10.1016/j.psychres.2004.05.007

Genes

DRD4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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