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Article

Inheritance of lysosomal acid beta-galactosidase activity and gangliosides in crosses of DBA/2J and knockout mice.

Biochemical genetics - 1 Aug 2004

Hauser Eric C, Kasperzyk Julie L, d'Azzo Alessandra, Seyfried Thomas N

Abstract excerpt

GM1 gangliosidosis is a progressive neurodegenerative disease caused by deficiencies in lysosomal acid beta-galactosidase (beta-gal) and involves accumulation and storage of ganglioside GM1 and its asialo form (GA1) in brain and visceral tissues. Similar to the infantile/juvenile human disease fo...

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Source

Identifiers

PMID: 15487588
DOI: 10.1023/b:bigi.0000034429.55418.71

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15487588-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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