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Article

Impact of beta-galactosidase mutations on the expression of the canine lysosomal multienzyme complex.

Biochimica et biophysica acta - 1 Oct 2009

Kreutzer Robert, Kreutzer Mihaela, Sewell Adrian C, Techangamsuwan Somporn, Leeb Tosso, Baumgärtner Wolfgang

Abstract excerpt

beta-galactosidase (GLB1) forms a functional lysosomal multienzyme complex with lysosomal protective protein (PPCA) and neuraminidase 1 (NEU1) which is important for its intracellular processing and activity. Mutations in the beta-galactosidase gene cause the lysosomal storage disease G(M1)-gangliosidosis. In order to identify additional molecular changes associated with the presence of beta-galactosidase...

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Source

Identifiers

PMID: 19607915
DOI: 10.1016/j.bbadis.2009.07.004

Genes

GLB1
NEU1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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