Article
[Gene-gene and gene-environment interactions as modifier factors of prostatic cancer risk: "a case-only" design study].
Revista medica de Chile - 1 Aug 2004
Cáceres Dante, Iturrieta Jeannette, Acevedo Cristian, Huidobro Christian, Varela Nelson, Escala Mario, Quiñones Luis
Abstract excerpt
BACKGROUND: The role of susceptibility low penetrance genes and environmental factors in the etiology of prostate cancer (PCa) is unclear, but may involve in some cases multiple alleles at multiple loci. AIM: To evaluate the association of gene-gene and gene-environment interactions with PCa. PATIENTS AND METHODS: One hundred three subjects with biopsy proven PCa were studied, using a case-only design. All were...
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