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Article

Screening selected blood donors with biochemical iron overload for hemochromatosis: a regional experience.

Haematologica - 1 Oct 2004

De Gobbi Marco, D'Antico Sergio, Castagno Franco, Testa Domenico, Merlini Roberta, Bondi Alessandro, Camaschella Clara

Abstract excerpt

BACKGROUND AND OBJECTIVES: Hemochromatosis is a genetic disorder characterized by progressive iron overload which leads to early abnormalities of iron parameters (increased transferrin saturation =TS and serum ferritin=SF) and late clinical complications. The disease is prevalently due to C282Y and H63D mutations in the HFE gene, but additional molecular defects are present in a minority of patients. DESIGN AND...

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Source

Identifiers

PMID: 15477198

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Screening selected blood donors with biochemical iron overload for hemochromatosis: a regional experience.PMID 15477198Read ↗

Mutations of the hemochromatosis gene in Italian candidate blood donors with increased transferrin saturation.Semantic proximity Read ↗

Analysis of HFE and TFR2 mutations in selected blood donors with biochemical parameters of iron overload.Semantic proximity Read ↗

Population screening for hemochromatosis: a study in 5370 Spanish blood donors.Semantic proximity Read ↗

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy.Semantic proximity Read ↗

Clinical utility and outcome of HFE-genotyping in the search for hereditary hemochromatosis.Semantic proximity Read ↗

Hereditary hemochromatosis: population screening based on phenotype in Brazilian blood donors.Semantic proximity Read ↗

Evaluation of a screening program for iron overload and HFE mutations in 50,493 blood donors.Semantic proximity Read ↗

Epidemiology and diagnostic testing for hemochromatosis and iron overload.Semantic proximity Read ↗

Diagnosis and management of hereditary hemochromatosis: lifestyle modification, phlebotomy, and blood donationSemantic proximity Read ↗

Screening for Hemochromatosis: High Prevalence and Low Morbidity in an Unselected Population of 65,238 PersonsSemantic proximity Read ↗

HFE genotype and parameters of iron metabolism in German first-time blood donors - evidence for an increased transferrin saturation in C282Y heterozygotes.Semantic proximity Read ↗

The Southern French registry of genetic hemochromatosis: a tool for determining clinical prevalence of the disorder and genotype penetrance.Semantic proximity Read ↗

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