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Article

Population screening for hemochromatosis: a study in 5370 Spanish blood donors.

Journal of hepatology - 1 Jun 2003

Sánchez Mayka, Villa Margarita, Ingelmo Mercedes, Sanz Cristina, Bruguera Miquel, Ascaso Carlos, Oliva Rafael

Abstract excerpt

BACKGROUND/AIMS: Hereditary hemochromatosis is associated with homozygosity for C282Y mutation in the HFE gene, elevated serum transferrin saturation and excess iron deposits throughout the body. We conducted a population-based study in Spain to asses the prevalence of the HFE mutations and their effect on iron parameters. METHODS: We screened 5370 blood donors for the C282Y and H63D HFE mutations by...

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Source

Identifiers

PMID: 12763366
DOI: 10.1016/s0168-8278(03)00123-5

Genes

HFE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Population screening for hemochromatosis: a study in 5370 Spanish blood donors.PMID 12763366Read ↗

HFE genotype and parameters of iron metabolism in German first-time blood donors - evidence for an increased transferrin saturation in C282Y heterozygotes.Semantic proximity Read ↗

Analysis of HFE and TFR2 mutations in selected blood donors with biochemical parameters of iron overload.Semantic proximity Read ↗

Clinical utility and outcome of HFE-genotyping in the search for hereditary hemochromatosis.Semantic proximity Read ↗

Frequency and biochemical expression of C282Y/H63D hemochromatosis (HFE) gene mutations in the healthy adult population in Italy.Semantic proximity Read ↗

Mutations of the hemochromatosis gene in Italian candidate blood donors with increased transferrin saturation.Semantic proximity Read ↗

C282Y and H63D mutation frequencies in a population from central Spain.Semantic proximity Read ↗

[Genotype and phenotypic expression of hereditary hemochromatosis in Spain].Semantic proximity Read ↗

Screening selected blood donors with biochemical iron overload for hemochromatosis: a regional experience.Semantic proximity Read ↗

Mutations in the HFE gene (C282Y, H63D, S65C) in a Brazilian populationSemantic proximity Read ↗

Evaluation of a screening program for iron overload and HFE mutations in 50,493 blood donors.Semantic proximity Read ↗

Correlation between iron status and genetic hemochromatosis (codon C282Y) in a large German population.Semantic proximity Read ↗

HFE-associated hereditary hemochromatosis.Semantic proximity Read ↗

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