Novel Real-Time PCR Assay for Detection of <i>Helicobacter pylori</i> Infection and Simultaneous Clarithromycin Susceptibility Testing of Stool and Biopsy Specimens

Abstract excerpt

A biprobe real-time PCR protocol, followed by hybridization melting point analysis, to detect point mutations in the 23S rRNA gene of Helicobacter pylori associated with clarithromycin resistance was established and evaluated in a clinical study. Of 92 patients who underwent endoscopy, 45 were found to be H. pylori infected and invariably were also culture positive. Of the 45 isolates, 11 were shown to be...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Gastric Cancer Management and Outcomes
• Share to Helicobacter pylori-related gastroenterology studies
• Share to Veterinary medicine and infectious diseases