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Rapid Detection of Mutations in the 23S rRNA Gene of <i>Helicobacter pylori</i> That Confers Resistance to Clarithromycin Treatment to the Bacterium

1 Feb 2001

Abstract excerpt

We developed a new method capable of detecting point mutations in the 23S rRNA gene of Helicobacter pylori using a LightCycler. Our method can detect a mutation in this gene in less than 1 h and can process many samples at once, thereby contributing to the selection of patients suitable for clarithromycin-based therapy.

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PMID: 11158129
DOI: 10.1128/jcm.39.2.691-695.2001

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