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Article

MMTV-trBrca1 mice display strain-dependent abnormalities in vaginal development.

The International journal of developmental biology - 1 Sept 2004

Simpson Kaylene J, Wati Mas R, Deans Andrew J, Lindeman Geoffrey J, Brown Melissa A

Abstract excerpt

The breast cancer susceptibility gene Brca1 encodes a large multi-functional protein which is implicated as a caretaker of the genome, through its role in regulation of DNA damage response pathways, including apoptosis. Here we show that in mice expressing a dominant-negative Brca1 transgene on a...

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Share to Dose-Response Relationship, Radiation
Share to Genes, BRCA1
Share to Mammary Glands, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mammary Neoplasms, Animal

Share to Mammary Tumor Virus, Mouse

Share to Mice, Inbred CBA

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Source

Identifiers

PMID: 15470641
DOI: 10.1387/ijdb.041849ks

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-15470641-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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