Article
Early activation or "priming" of eosinophils in asthma.
Schweizerische medizinische Wochenschrift - 29 Feb 1992
Bruijnzeel P L, Rihs S, Virchow J C, Warringa R A, Moser R, Walker C
Abstract excerpt
Increased numbers of blood and tissue eosinophils are regularly observed in subjects suffering from bronchial asthma. The eosinophil number in the diseased organ is normally closely associated with the presence of clinical symptoms. Not only the cell number, but also the concentration of eosinophil-granule derived mediators is increased in the diseased organ. In particular toxic proteins released by the...
Topics
- Asthma
- Cell Movement
- Eosinophils
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- Interleukin-3
- Interleukin-5
- Phenotype
- SRS-A
