Article
Expression of activated Fc gamma RII discriminates between multiple granulocyte-priming phenotypes in peripheral blood of allergic asthmatic subjects.
The Journal of allergy and clinical immunology - 1 Nov 2007
Kanters Deon, ten Hove Willem, Luijk Bart, van Aalst Corneli, Schweizer René C, Lammers Jan-Willem J, Leufkens Hubert G M, Raaijmakers Jan A M, Bracke Madelon, Koenderman Leo
Abstract excerpt
BACKGROUND: Allergic asthma is associated with chronic airway and systemic immune responses. Systemic responses include priming of peripheral blood eosinophils, which is enhanced after allergen challenge. In a subpopulation of asthmatic subjects, neutrophils are associated with bronchial inflammation. OBJECTIVE: We sought to monitor systemic granulocyte priming in allergic asthmatic subjects as a consequence of...
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