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Article

The amino acid transporter asc-1 is not involved in cystinuria.

Kidney international - 1 Oct 2004

Pineda Marta, Font Mariona, Bassi Maria Teresa, Manzoni Marta, Borsani Giuseppe, Marigo Valeria, Fernández Esperanza, Río Rafael Martín del, Purroy Jesús, Zorzano Antonio, Nunes Virginia, Palacín Manuel

Abstract excerpt

BACKGROUND: The human amino acid transporter asc-1 (SLC7A10) exhibits substrate selectivity for small neutral amino acids, including cysteine, is expressed in kidney, is located close to the cystinuria B gene and presents sequence variants (e.g., E112D) in some cystinuria patients. We have cloned human asc-1, assessed its transport characteristics, localized its expression in kidney, searched for mutations in...

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PMID: 15458438
DOI: 10.1111/j.1523-1755.2004.00908.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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