Article
Prediction of curve progression in idiopathic scoliosis from gene polymorphic analysis.
Studies in health technology and informatics - 1 Jan 2002
Inoue Masatoshi, Minami Shohei, Nakata Yoshinori, Takaso Masashi, Otsuka Yoshinori, Kitahara Hiroshi, Isobe Keijiro, Kotani Toshiaki, Maruta Tetsuro, Moriya Hideshige
Abstract excerpt
Three hundred and four girls with adolescent idiopathic scoliosis were investigated to determine if DNA polymorphisms in the vitamin D receptor (VDR), estrogen receptor (BR), and CYP17 gene were related to curve progression of idiopathic scoliosis. The results suggested that XbaJ site polymorphism in the ER gene was associated with curve progression. The Cobb's curve angle with genotype XX and Xx was...
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