Article
Role of a bacterial organic hydroperoxide detoxification system in preventing catalase inactivation.
The Journal of biological chemistry - 10 Dec 2004
Wang Ge, Conover Richard C, Benoit Stephane, Olczak Adriana A, Olson Jonathan W, Johnson Michael K, Maier Robert J
Abstract excerpt
In the gastric pathogen Helicobacter pylori, catalase (KatA) and alkyl hydroperoxide reductase (AhpC) are two highly abundant enzymes that are crucial for oxidative stress resistance and survival of the bacterium in the host. Here we report a connection unidentified previously between the two stress resistance enzymes. We observed that the catalase in ahpC mutant cells in comparison with the parent strain is...
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