Article
Toward a theory of marker-assisted gene pyramiding.
Genetics - 1 Sept 2004
Servin Bertrand, Martin Olivier C, Mézard Marc, Hospital Frédéric
Abstract excerpt
We investigate the best way to combine into a single genotype a series of target genes identified in different parents (gene pyramiding). Assuming that individuals can be selected and mated according to their genotype, the best method corresponds to an optimal succession of crosses over several generations (pedigree). For each pedigree, we compute the probability of success from the known recombination fractions...
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