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Article

Effect of latanoprost on intraocular pressure in mice lacking the prostaglandin FP receptor.

Investigative ophthalmology & visual science - 1 Oct 2004

Crowston Jonathan G, Lindsey James D, Aihara Makoto, Weinreb Robert N

Abstract excerpt

PURPOSE: To determine whether latanoprost lowers IOP in prostaglandin FP receptor knockout mice. METHODS: Mean IOP difference between treated and untreated fellow eyes was measured on three separate occasions, 2 hours after a 200-ng dose of latanoprost to the right eye of homozygous (n = 9) and heterozygous (n = 15) FP knockout mice. C57BL/6 (n = 10) and NIH Swiss white mice (n = 17), which have normal FP...

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Source

Identifiers

PMID: 15452062
DOI: 10.1167/iovs.04-0338

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Effect of latanoprost on intraocular pressure in mice lacking the prostaglandin FP receptor.PMID 15452062Read ↗

Stanniocalcin-1 (STC-1), a downstream effector molecule in latanoprost signaling, acts independent of the FP receptor for intraocular pressure reduction.Semantic proximity Read ↗

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Identification and pharmacological characterization of the prostaglandin FP receptor and FP receptor variant complexes.Semantic proximity Read ↗

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