Article
Acquired radioresistance of hematopoietic progenitors (granulocyte/monocyte colony-forming units) during chronic radiation leukemogenesis.
Cancer research - 15 Mar 1992
Seed T M, Kaspar L V
Abstract excerpt
Protracted exposure of dogs to low daily doses of whole-body gamma-radiation (7.5 cGy/day for duration of life) elicits a high incidence of myeloid leukemia or related myeloproliferative disorders. Under such exposure, vital hematopoietic progenitors [granulocyte/monocyte colony-forming units in...
Topics
- Animals
- Dogs
- Dose-Response Relationship, Radiation
- Granulocytes
- Hematopoietic Stem Cells
- Incidence
- Leukemia, Radiation-Induced
- Monocytes
- Myeloproliferative Disorders
- Phenotype
- Radiation Dosage
- Radiation Tolerance
- Whole-Body Irradiation
