Effect of combined cortisol-endotoxin administration on peripheral blood leukocyte counts and phenotype in normal humans.

doi:10.1001/archsurg.1992.01420020067010

Back to search

Article

Effect of combined cortisol-endotoxin administration on peripheral blood leukocyte counts and phenotype in normal humans.

Archives of surgery (Chicago, Ill. : 1960) - 1 Feb 1992

Calvano S E, Barber A E, Hawes A S, de Riesthal H F, Coyle S M, Lowry S F

Abstract excerpt

We studied the role of lipopolysaccharide and the associated hypercortisolemic response as mediators of leukocyte changes associated with endotoxemia. Normal human subjects were given continuous, 12-hour, intravenous infusions of cortisol. After 6 hours of cortisol infusion, lipopolysaccharide (2...

Topics

Adult
Endotoxins
Humans
Hydrocortisone
Leukocyte Count
Leukocytes
Lipopolysaccharides
Lymphocyte Subsets
Male
Phenotype

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.