Article
Dopamine receptor gene polymorphisms in Parkinson's disease patients reporting "sleep attacks".
Movement disorders : official journal of the Movement Disorder Society - 1 Nov 2004
Rissling Ida, Geller Frank, Bandmann Oliver, Stiasny-Kolster Karim, Körner Yvonne, Meindorfner Charlotte, Krüger Hans-Peter, Oertel Wolfgang H, Möller J Carsten
Abstract excerpt
Genes encoding proteins involved in dopaminergic transmission are potential candidate genes for the induction of somnolence in Parkinson's disease (PD) because dopaminergic agents have been shown to be associated with sudden onset of sleep (SOS) in PD. We conducted an association study on dopamine D2, D3, and D4 receptor gene polymorphisms comparing 137 PD patients with SOS and 137 PD patients without SOS matched...
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