Article
Hyperhomocysteinemia and vitamin B6 deficiency: new risk markers for nonvalvular atrial fibrillation?
American heart journal - 1 Sept 2004
Marcucci Rossella, Betti Irene, Cecchi Emanuele, Poli Daniela, Giusti Betti, Fedi Sandra, Lapini Ilaria, Abbate Rosanna, Gensini Gian Franco, Prisco Domenico
Abstract excerpt
BACKGROUND: A recent "ex-vivo" study showed that nonvalvular atrial fibrillation (NVAF) is associated with enhanced activity of metalloproteinases at the atrial level, and in animal models homocysteine (Hcy) is able to activate metalloproteinases. The aim of this case-control study was to investigate the association of total Hcy plasma levels, vitamin status (folate, vitamin B6, and vitamin B12), and...
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